Neurologic Dark Matter: Exploring the Exposome that Drives Neurological Disorders

Presidential Symposium

Date/Time: Sunday, October 23, 2022 - 1:15 PM – 3:15 PM
Track: Plenary Session
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Description:

Recent and emerging research is revealing the exquisite sensitivity of the nervous system to environmental toxicants. The exposome refers to all of an individual’s environmental exposures — chemicals but also factors such as psychological stress and diet — experienced during the lifespan. Environmental neurotoxicology is a relatively new scientific area, whereas pollutants and other exposures have long been studied for their roles in neurodevelopment, other organ systems, immune disorders, and cancer. This plenary has been inspired by a recent Nataional Academy of Medicine Neuroscience Forum (link) and will provide an overview of what is known about neurotoxic exposures and how they lead to not only to neurodevelopmental but a wide range of neurological and neurodegenerative disorders. This symposium will also consider the consequences on public health and health disparities, and discuss research gaps and collaborative opportunities between neuroscientists and environmental health scientists.

Chair: Frances E. Jensen, MD, FANA

Moderator: Walter J. Koroshetz, MD

Moderator: Rick Woychik, PhD

Objectives:

  • Understand the role of environmental chemical exposure on neurodevelopmental disorders and neurodegenerative diseases.    
  • Recognize how the convergence of social disadvantage and pollutant exposures impacts the higher risk of disease. 
  • Identify research gaps and collaborative opportunities between neuroscientists and environmental health scientists.

Chemical Exposures: The Ignored Environmental Risk Factor(s) for Neurodegenerative Diseases and Neurodevelopmental Disorders 

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Racial Disparities in Exposures to Environmental Contaminants

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Leveraging the Exposome for ALS Prevention

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Convergent Mechanisms of Environmental Toxicant-Induced Parkinson’s Disease

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Is the Rise in Incidence of Parkinson’s Largely Human-Made?

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