Neuroinflammation and Neuroinfection

Date/Time: Sunday, October 23, 2022 - 3:30 PM – 5:30 PM
Track: Cross-Cutting Special Interest Group
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As the first session of the new Neuroinflammation and Neuroinfection SIG, we will introduce concepts of how inflammation in the nervous system associates with neurological injury and clinical disease, and review state of the art methods now available to interrogate these questions using a variety of methods in humans and animal models.  We will use the timely of neurologic effects of SARS-CoV-2 and HIV-1 as central examples of how inflammation and immune activation in response to a pathogen may lead to clinical disease, how this may be investigated, and future areas for research and clinical intervention relevant to these and other neuroinflammatory states. 

Chair: Serena Spudich, MD, MA

Co-Chair: Kiran Thakur, MD

Central Nervous System Impact of Acute and Long COVID


CSF Biomarkers of Neuroinflammation, Neuronal Injury, and Amyloid Processing in Infectious Disease


Cellular CNS Immune Activation/Neuroinflammation in HIV/SHIV


Novel Multiomics Assessment of Neuroinflammation in HIV & COVID-19


RT-QuIC Testing for Prions: Applying a Sensitive but Imperfect Test in Clinical Practice

Poster Presenter: Sam Jones

A Multi-Institutional Collaboration for Deep Phenotyping of Undiagnosed Neuroinflammatory and Neuroinfectious Diseases

Poster Presenter: Yair Mina, MD, National Institutes of Health (NIH)

Blood-CSF-Barrier Permeability in Tuberculous Meningitis and Its Association with Clinical, MRI and Inflammatory Cytokines

Poster Presenter: Ruchi Shukla, PhD