Neurodegeneration and Cell Death

Date/Time: Sunday, October 23, 2022 - 3:30 PM – 5:30 PM
Track: Cross-Cutting Special Interest Group
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Description:

Many recent advances have been made in the field of neurodegeneration that will impact our ability to diagnose, treat and prevent neurodegenerative diseases like Alzheimer’s Disease, Parkinson’s Disease, frontotemporal dementia and Huntington’s Disease. Proteinaceous inclusions were once thought to be viable targets in these diseases. We now know that they serve as excellent biomarkers, but that upstream mechanisms need to be targeted for effective therapeutics. This session will focus on the basic science and translational advances that have made recently.

Chair: Aimee W. Kao, MD, PhD, FANA

Co-Chair: Alice Chen-Plotkin, MD, PhD, FANA

Objectives:

  • Be able to describe new tools for detecting cell death and neurodegeneration, that could serve as biomarkers for future therapeutic trials
  • Understand the genes and molecules that contribute to neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Huntington’s Disease
  • Gain up-to-date knowledge on the basic and translational investigations in neurodegeneration, and future potential therapeutics

Cell Death - Its Importance in Neurodegenerative Disease, and New Technologies to Predict it in Time to Intervene

Speaker:


How Do We Get From GWAS locus to Therapeutic Target in Parkinson's Disease?

Speaker:


Tangled Tau - Live Free or Die

Speaker:


Synucleionopathy-Associated Microglia Uncovered by a Novel Multiple System Atrophy-Cerebellar Type (MSA-c) Mouse Model

Poster Presenter: Kira Jun-ichi, MD, PhD, International University of Health and Welfare


Integrative Whole Brain and Neuron-Specific Native-State Proteomics Identifies Molecular Vulnerabilities of PV Interneurons

Poster Presenter: Srikant Rangaraju, MD, MS, Emory University School of Medicine


 

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