Neurocritical Care and Traumatic Brain Injury

Date/Time: Monday, October 24, 2022 - 3:45 PM – 5:45 PM
Track: Traditional Special Interest Group
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Biomarker (fluid-based, imaging, electrophysiological) research in neurocritical care has significantly expanded over the last decade, but there has been incomplete adoption of biomarkers due to several distinct factors. Not all modalities are readily available in all clinical settings (advanced imaging, labs equipped to test for certain biomarkers), or there may be considerable delay in obtaining this information if it is available (e.g. neuron specific enolase after cardiac arrest). Clinicians are not always knowledgeable about what biomarkers are under investigation versus which are validated. In parallel, there is a knowledge gap regarding what circumstances and the timing surrounding multimodal prognostication. This session will explore the emerging use of biomarkers and prediction of long term outcomes in adults and children after acute neurologic injury.

Chair: H.E. (Holly) Hinson, MD, MCR

Co-Chair: Marion Buckwalter, MD, PhD


  • Learners will identify ancillary testing that may provide assistance with long term prognostication in acute neurological injury (e.g. TBI, cardiac arrest, etc.)
  • Learners will distinguish between validated and promising emerging biomarkers of long-term prognosis after traumatic brain injury (TBI) 
  • Attendees will define Post-Pediatric Intensive Care Unit Syndrome and identify emerging prognostication methods in children suffering acute, severe neurologic injury

Post-Pediatric Intensive Care Unit Syndrome and Long-Term Outcomes


Long Term Prognosis after Cardiac Arrest Incorporating Imaging Biomarkers


Long-term Prognosis after Traumatic Brain Injury—Novel Biomarker Insights


Discrepancy Between Surrogate Estimated and Observed Patient Outcomes After Severe Stroke

Poster Presenter: Roland Faigle, MD, PhD, Johns Hopkins University School of Medicine

Repeated Mild Traumatic Brain Injury is an Exogenous Trigger for Neurodegeneration in Transgenic Mice Expressing Human C9orf72 Hexanucleotide Repeat Expansions

Poster Presenter: Aydan Kahriman, MD, University of Massachusetts Medical School